![]() ![]() The normal serum creatinine ( sCr) varies with the subject's body muscle mass and with the technique used to measure it. In contrast, the rugged rancher who eats in excess of 125 g protein each day may have a normal BUN of 20 mg/dl. Her higher glomerular filtration rate (GFR), expanded extracellular fluid volume, and anabolism in the developing fetus contribute to her relatively low BUN of 5 to 7 mg/dl. A BUN of 15 mg/dl would represent significantly impaired function for a woman in the thirtieth week of gestation. The range is wide because of normal variations due to protein intake, endogenous protein catabolism, state of hydration, hepatic urea synthesis, and renal urea excretion. ![]() The normal range of urea nitrogen in blood or serum is 5 to 20 mg/dl, or 1.8 to 7.1 mmol urea per liter. The BUN, then, is roughly one-half (28/60 or 0.446) of the blood urea. In Europe, the whole urea molecule is assayed, whereas in the United States only the nitrogen component of urea (the blood or serum urea nitrogen, i.e., BUN or SUN) is measured. Both are relatively small molecules (60 and 113 daltons, respectively) that distribute throughout total body water. Creatinine is the product of muscle creatine catabolism. Urea is the primary metabolite derived from dietary protein and tissue protein turnover. The nurse should report this value to the provider as it may require further evaluation and treatment.Urea and creatinine are nitrogenous end products of metabolism. A high BUN level can indicate dehydration, kidney failure, urinary tract obstruction, heart failure, or excessive protein intake. A normal BUN level does not necessarily rule out dehydration, as other factors such as diet, medications, and blood loss can affect the BUN level.Ĭhoice D: 25 mg/dL is correct because it is above the normal range of BUN and indicates a high BUN level. A low BUN level can indicate liver problems, malnutrition, or overhydration.Ĭhoice C: 13 mg/dL is incorrect because it is also within the normal range of BUN. BUN can reflect the kidney function and hydration status of the client.Ĭhoice B: 10 mg/dL is incorrect because it is also within the normal range of BUN. BUN stands for blood urea nitrogen, which is a measure of the amount of nitrogen in the blood that comes from urea, a waste product of protein metabolism.
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